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Anastomotic leakage and stenosis after surgery for esophageal atresia is not related to the development of late functional sequelae (Abstract)

Kamilla Wodstrup Rost¹, Niels Qvist¹ & Rikke Neess Pedersen²

¹Surgical Department A and  ²Hans Christian Andersen Children’s Hospital, Odense University Hospital, Denmark


Purpose: The aims of the present study were to evaluate the relationship between postoperative complications as anastomotic leakage and stricture and late sequelae in patients operated for esophageal atresia, and to evaluate the frequency of dyspepsia and recurrent abdominal pain in children operated for esophageal atrsia compared to a background population.

Materials and methods: Medical records from sixty-two consecutive children operated for esopha geal atresia with primary anastomosis in the period from 1990-2000 were reviewed and a  follow-up questionnaire sent to the patients. The age at follow-up was 10.3 years (range 6-16 years).

Results: Perioperative anastomotic leakage occurred in 13% and symptomatic stricture in 73%. At follow-up late sequlae such as gastro-esophageal reflux disease was reported in 31%, pneumo-nia in 40%, asthmatic bronchitis in 27% and asthma in 8%. There were no significant correlation between late sequelae and postoperative complications. From the questionnaire dyspepsia was reported in 35% of patients operated for esophageal atresia compared to 5% in the background population (p<0.0001).

Conclusion: Further extensive physiological studies are needed to explore and explain the physi-ologic background for the high frequency of late sequelae in patients operated for esophageal atresia.


Keywords: esophageal atresia, anastomotic leakage, anastomotic stenosis, dyspepsia, recurrent abdominal pain, gastro-esophageal reflux, gastro-esophageal reflux disease


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